Abstract: A novel asymmetric bianthracene derivative was designed and synthesized. Then the response properties were investigated. The emission properties of the derivative in different solvents indicated that when the solvent polarity increased, the spectrum shifted to red. This revealed that it had strong intramolecular charge transfer characteristics, mainly originating from the twisted intramolecular charge transfer of the bianthracene group. The acid response showed that after acid fumigation, the fluorescence spectrum shifted to red by 61 nm, and it could be restored after alkali fumigation. This process is repeatable. This was mainly attributed to the enhancement of intramolecular charge transfer properties caused by the protonation of pyridine nitrogen. In addition, the compound exhibited mechanochromism. The spectrum after grinding shows a redshift of 16 nm and broadening of half-peak width, which can be recovered after exposure to the hexane fumigation. When stimulated by pressure, the twist angle between the bianthryl groups may undergo stimulated adjustment, thereby affecting the intramolecular conjugation state. At the same time, force stimulation changes the interaction between molecules, resulting in a red shift in luminescence.