Abstract: To investigate the ecological effects of Galaxolide （HHCB） and cadmium （Cd） on carrot plants, a pot experiment was conducted to study the accumulation, subcellular distribution, and health risk assessment of these two pollutants. The results showed that the coexist of HHCB and Cd can mitigate the toxic effects of single pollutants on carrot plants, and the biomass and chlorophyll content in the joint pollution treatments were higher than those in the single pollution treatments. At the joint pollution of 1 mg·kg⁻¹ HHCB and 10 mg·kg⁻¹ Cd, Cd significantly promoted the accumulation of HHCB in the shoot and root of carrot plants, with promotion rates of 3.32%~26.37% and 1.07%~16.80%, respectively. HHCB also promoted the accumulation of Cd with high concentration in the plants. The subcellular distribution proportions of HHCB and Cd were different in the carrot plants. The subcellular distribution proportions of HHCB in cell organelles, cell wall and cell soluble constituent were 16.60%~82.93%, 3.64%~41.64% and 10.96%~61.94%, respectively. But the subcellular distribution proportions of Cd in cell organelles, cell wall and cell soluble constituent were 1.69%~8.65%,55.76%~84.12% and 11.60%~29.49%, respectively. The coexist of HHCB and Cd affected their subcellular distribution in the plants. Through the target hazard quotient assessment, the health risk to adults and children from consuming carrots grown in farmlands contaminated by HHCB and Cd was significant and was mainly induced by Cd pollution. This study provides data support for the ecological effect, subcellular distribution and health risk of the joint pollution with organic pollutant and heavy metal in soil-plant system.